Her family announced her death in a social media post shared by the John F Kennedy Library Foundation, writing: "Our beautiful Tatiana passed away this morning. She will always be in our hearts." In November, Schlossberg, a climate journalist, announced her diagnosis of an aggressive form of cancer. She said in an essay that she had been given less than a year to live. Schlossberg was the daughter of designer Edwin Schlossberg and diplomat Caroline Kennedy, and is survived by her husband George Moran and their two children, three-year-old Edwin and one-year-old Josephine.

In an article published  in The New Yorker titled, "A Battle With My Blood," Schlossberg revealed she had been diagnosed with acute myeloid leukaemia in May 2024, after giving birth to her second child. "My first thought was that my kids, whose faces live permanently on the inside of my eyelids, wouldn't remember me," she wrote.

Schlossberg described the treatments she received, including chemotherapy and a bone marrow transplant, but shared that doctors did not give her a good prognosis. She also wrote of the pain she feared her passing would cause for her family, which has endured multiple personal tragedies. Her grandfather, President Kennedy, was assassinated in 1963 and her uncle, John F Kennedy Jr, died in a plane crash in 1999. Her younger brother, Jack Schlossberg, is running for Congress in New York. "For my whole life, I have tried to be good, to be a good student and a good sister and a good daughter, and to protect my mother and never make her upset or angry," Schlossberg wrote. "Now I have added a new tragedy to her life, to our family's life, and there's nothing I can do to stop it," she said. (BBC)